The first over the counter and FDA approved weight loss drug is not producing the impact that was projected it may be due to several factors. The poor economic status may have people skipping buying a pill and opting for the traditional exercise and diet approach which is the best approach if you are willing to motivate yourself to do it.

So why are sales low? Let's talk about what Alli is first. The drug was approved in 2007 for over-the-counter marketing as a weight loss aid. Glazosmithkline, the creators of Alli, recommend the drug be used with a diet low in fat, a daily multivitamin, and exercise program.

Glaxosmithkline spent 150 million on marketing campaigns for Alli during its first year. Their marketing campaign has focused on the Alli plan. The plan is to live life in a new way with adjustments to eating habits and exercise regimen. The marketing plan seemed to miss the mark. The original sales projections were 5 to 6 million annually, but Alli’s first year was short a million. The company says the product is not for everyone, but is an option and can help to increase weight loss by 50 percent. (During clinical trials, 2 to 3 pounds for every 5 pounds lost through diet and exercise was reported lost in patients using Alli, although almost half of the patients involved in the trial reported gastrointestinal side effects.)

Alli prevents absorption of a quarter of fat that is eaten. One fat gram has double the calories of protein and carbohydrates. Therefore, while taking Alli and eating a reduced calorie low fat diet Glaxosmithkline feels Alli could really make a difference in weight while limiting the total calories entering the system. However, Alli pamphlets state that the drug is only expected to help lose 5 to 10 pound in 6 months. Some dieters feel the small amount of weight loss could be accomplished by cutting out a few soft drinks weekly without taking the diet pill

Alli’s side effects of leakages and oily discharge that can cause soiled underwear can be deterring. Prior to the drug launch there was marketing materials for the new drug that stressed the importance of keeping meals under 15 grams of fat to avoid soiled underwear. Some pamphlets even recommended starting the program when off of work. Now the company has began to state that the side effects can be avoided with the proper use of the drug.

Why would the 1st FDA-approved weight loss drug not blow the projected numbers out of sight? It could be because change is a challenge for most people and the company recommends that anyone taking the pill also adopts exercise and good low-fat eating habits.

New Breast Imaging machine is making detecting breast cancer easier. This is good news because identifying cancer earlier is essential to increase survival rate. Considering Breast cancer is very common in women and occurs occasionally in men it is important to note that this is great news for our health.

Results which recognized mammography as a successful diagnostic tool for cancer were first published in 1967. Since that time, breast self-examination and a mammography have been considered essential in the identification of breast cancer. The goal of mammograms is the early detection of breast cancer, but this technique has not always been reliable, with false positive and false negative readings occurring in a portion of cases.

Doctors are now using newer breast imaging techniques to diagnose and stage breast cancer. Breast-specific gamma imaging (BSGI) and positron emission mammography (PEM) rely on the use of radiotracers to detect cancer cells instead of the X-rays used in mammograms. The BSGI tracer is positively charged, while cancer cells are negatively charged. The tracer diffuses around cancer cells and highlights them in the process. The PEM tracer uses glucose in this process. Glucose is used by all cells for energy, with cancer cells using more energy and more of the tracer which are highlighted on the image.

Dr. Patrick Borgen, director of the Brooklyn Breast Cancer Program at the Maimonides Cancer Center in Brooklyn, N.Y. said, “I think it’s exciting that we’re moving more to functional imaging, but mammography is the mainstay of breast cancer screening and neither of these tests is in a position to replace mammography as the cornerstone of cancer detection. These tests are adjuncts.” Borgen, who was not involved in studies involving either BSGI of PEM procedures, stated that neither test is widely available and both can be costly.

Studies of both procedures and their results were presented at the annual meeting of the Radiological Society of North America held November 30th to December 5th in Chicago. In one of the studies PEM was used to assess how the imaging technique was affected by the density of breasts or the hormonal status of the patient in 208 women with breast cancer. Dr. Kathy Schilling, director of breast imagining and intervention at the Center for Breast Care at the Boca Raton Community Hospital in Florida said that the PEM scanner does immobilize the breast, but does not compress it. Schilling was the lead author of the study. Schilling said the results were similar to, or better than, breast MRI tests. She believes that the PEM will probably be used as breast MRI’s have been used, because MRI causes so many false positives and unnecessary biopsies.


The second study, reviewed data from 159 women who had been found to have a suspicious lesion as a result of a mammogram. The women then had BSGI scanning which uses mild compression to capture images. The testing revealed suspicious lesions in 29 percent of the women, a third of these lesions were found to be cancerous. This study was conducted by Rachel F. Brem, M.D., of the George Washington University Medical Center in Washington DC, and colleagues.

Breast cancer in women is second only to skin cancer for incidence in the United States. Experts agree that the best way to decrease mortality from the disease is through early detection.